PV-0048: Prognostic impact of tumor size and response in neoadjuvant radiotherapy of soft tissue sarcoma

Prognostic factors in soft tissue sarcoma

Prognostic Factors in Soft Tissue Sarcoma

Soft tissue sarcoma (STS) represents a heterogeneous group of mesenchymal malignant tumors with variable natural history. This term was first introduced to describe a circumscribed neoplasm consisting of malignant fat cell occurring principally in the trunk (Abernethy, 1817). Nowadays, more than 30 types of STS have been described, and many of these present innumerable subtypes. Despite this wi...

Prognostic factors in soft tissue sarcoma.

The ability to accurately define the prognosis for patients with soft tissue sarcoma is a continuing challenge. Classically, this has been accomplished through assessments of tumor size, histologic grade, location, and the presence of nodal or distant metastases. These criteria are the basis of the currently utilized American Joint Commission on Cancer (AJCC) staging system. However, several ot...

Prognostic variables in patients with primary soft tissue sarcoma of the extremity and trunk treated with neoadjuvant radiotherapy or neoadjuvant sequential chemoradiotherapy

BACKGROUND Neoadjuvant radiotherapy (NRT) is an effective strategy to treat soft tissue sarcomas (STS). However, the role of neoadjuvant chemoradiotherapy (NCRT) remains to be determined. METHODS From May 1999 to July 2010, 112 patients with localized STS of the extremity and trunk who were treated with NRT or NCRT followed by surgery were retrospectively reviewed. Clinical outcomes including...

Synovial Sarcoma of the Head and Neck: A Case of Childhood Soft Tissue Sarcoma

Although rare, synovial sarcoma is the most common malignant non-rhabdomyosarcomatous soft tissue sarcoma in children and adolescents. Synovial sarcoma typically involves the soft tissues of the extremities, especially near large joints, but it can occur anywhere in the body in locations far from joint spaces. Although this tumor typically affects adults in their fourth decade of life, nearly h...